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Lawrence Karsh

Dr. Karsh is a Certified Principal Investigator and the primary investigator of research studies at TUCC. He graduated from the Chicago Medical School and completed his General Surgical training at The University of Colorado Health Sciences Center under Dr. Thomas Starzl. He completed his Urology residency at Brigham and Women’s Hospital/Harvard Medical School under Dr. Ruben Gittes. He is a co-founder of The Urology Center of Colorado where he serves as an attending Urologist, Director of Research & Co-Chairman of Advanced Therapeutic Clinic. He has been the principle investigator for over 250 clinical trials.

Dr. Karsh has authored a number of peer-reviewed publications and serves on the editorial boards for Oncology Live, Urologist and Cancer Care, and Bladder Cancer. He is a fellow of the American College of Surgeons, and an active member AUA, SUO, ASCO, SWOG, ACS, and the Denver Academy of Surgeons. He served on the bladder cancer subcommittee and the advisory board for the SUO Clinical Trials Consortium from 2010-2020. He is a member of the Bladder Cancer Advocacy Network (BCAN) Think Tank.

Dr. Karsh completed his General Surgery training at The University of Colorado Health Sciences Center (UCHSC) and his Urology residency at Brigham and Women’s Hospital/Harvard Medical School. He is an associate clinical professor of surgery at UCHSC.Dr. Karsh serves as an advisor and consultant to the pharmaceutical industry, participating in drug development and research protocols. He educates physicians about newly approved therapies and he teaches at scientific meetings throughout the country.

In his spare time, Dr. Karsh is an avid road bicycler and skier.

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  • Genitourinary Oncology
  • Prostate Disease
  • Male Urinary Incontinence
  • Urinary Stone Disease
  • Clinical Research
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Key Accomplishments

  1. Director of Clinical Research at TUCC
  2. Elected Member of the Society of Urologic Oncology
  3. Editorial board member for OncologyLive Urologists in Cancer Care
  4. Has served as the Principal Investigator for more than 200 clinical research trials


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Men’s Pelvic Health Seminar 1/20/2021

Relating the Pelvic Floor to Pain and Other Problems Seminar Overview: The pelvic floor muscles and the relationships these muscles have to other parts of our body are important, and often overlooked contributors to low back pain, hip, perineum, and pelvic pain. Potential pelvic floor problems may manifest as follows: Persistent pain in the abdomen, hips,

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Dr. Kara K. Choate Joins TUCC

–TUCC CONTINUES TO BUILD ON ITS MISSION, EXCELLENCE IN UROLOGY – Kara Choate, M.D., has joined the team at The Urology Center of Colorado (TUCC). The TUCC team now includes 19 urologists, one radiation oncologist and five advanced practice providers. Dr. Choate completed her Urology Residency and General Surgery Internship at the University of Maryland Medical

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What Patient's Are Saying About Dr. Karsh

“Dr. Karsh went out of his way to explain my medical issue. My wife and I are very appreciative of him”

“Everyone was friendly, courteous and professional. You made me feel comfortable!”

“Extremely positive experience. The attention I received has been exemplary!”