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Lawrence Karsh

Dr. Karsh is a Certified Principal Investigator and the primary investigator of research studies at TUCC. He graduated from the Chicago Medical School and completed his General Surgical training at The University of Colorado Health Sciences Center under Dr. Thomas Starzl. He completed his Urology residency at Brigham and Women’s Hospital/Harvard Medical School under Dr. Ruben Gittes. He is a co-founder of The Urology Center of Colorado where he serves as an attending Urologist, Director of Research & Co-Chairman of Advanced Therapeutic Clinic. He has been the principle investigator for over 250 clinical trials.

Dr. Karsh has authored a number of peer-reviewed publications and serves on the editorial boards for Oncology Live, Urologist and Cancer Care, and Bladder Cancer. He is a fellow of the American College of Surgeons, and an active member AUA, SUO, ASCO, SWOG, ACS, and the Denver Academy of Surgeons. He served on the bladder cancer subcommittee and the advisory board for the SUO Clinical Trials Consortium from 2010-2020. He is a member of the Bladder Cancer Advocacy Network (BCAN) Think Tank.

Dr. Karsh completed his General Surgery training at The University of Colorado Health Sciences Center (UCHSC) and his Urology residency at Brigham and Women’s Hospital/Harvard Medical School. He is an associate clinical professor of surgery at UCHSC.Dr. Karsh serves as an advisor and consultant to the pharmaceutical industry, participating in drug development and research protocols. He educates physicians about newly approved therapies and he teaches at scientific meetings throughout the country.

In his spare time, Dr. Karsh is an avid road bicycler and skier.

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  • Genitourinary Oncology
  • Prostate Disease
  • Male Urinary Incontinence
  • Urinary Stone Disease
  • Clinical Research
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Key Accomplishments

  1. Director of Clinical Research at TUCC
  2. Elected Member of the Society of Urologic Oncology
  3. Editorial board member for OncologyLive Urologists in Cancer Care
  4. Has served as the Principal Investigator for more than 200 clinical research trials


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The Urology Center of Colorado Opens Lone Tree Location

–TUCC CONTINUES COMMITMENT TO COMMUNITY WITH EXCELLENCE IN UROLOGY – To further its commitment to all the communities around Denver, The Urology Center of Colorado (TUCC) is opening a new location in Lone Tree, Colorado. In order to better serve more patients in south Denver, TUCC is opening a new office located at 9695 S.

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Women’s Health – Urinary Incontinence 3/16/2021

Do you experience bladder leakage? Does it bother you? You’re not alone — and you have options for relief. One in 2 women suffer from urinary incontinence.* Do you: • Leak while laughing, sneezing, lifting or jumping? • Have trouble holding it as you hurry to the bathroom? • Wear pads or liners to protect

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Virtual OAB Discussion 2/10/2021

Approx. 1 in 6 Adults experience overactive bladder. That’s around 37 million adults in the US.* Did you know there are many ways to treat OAB and get back to living the life you want. Join Lisa Zwiers, PA-C at The Urology Center of Colorado and specialist at treating overactive bladder and incontinence, for a

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What Patient's Are Saying About Dr. Karsh

“Dr. Karsh went out of his way to explain my medical issue. My wife and I are very appreciative of him”

“Everyone was friendly, courteous and professional. You made me feel comfortable!”

“Extremely positive experience. The attention I received has been exemplary!”