Clinical advancements in the field of urology are featured in the news media every day. This section provides patients and physicians with the most up-to-date information on recent urologic advancements around the world.
* Please Note - TUCC does not necessarily advocate any of the treatment methods listed in the articles below. This news feed is provided as a resource for those interested in the latest urologic research occurring around the world.
A proposed simplere grading system for prostate cancer (PCa) can predict the risk of dying from PCa, according to a new study.
In the new system, PCa patients are placed into 1 of 5 grade groups based on primary and secondary Gleason score (GS) and other criteria, with Grade Group 1 indicating the most favorable prognosis and Grade Group 5 the least favorable. GS 6 cancers (3 + 3) are placed into Grade Group 1 and GS 7 cancers are subdivided into 3 + 4 and 4 + 3 disease. GS 3 + 4 cancers are associated with significantly better prognoses than GS 4 + 3 cancers and are placed into Grade Group 2 and 3, respectively. The new system also subdivides GS 8–10 cancers into GS 8 and GS 9–10 cancers.
Exercising during and after cancer treatment is safe and improves quality of life, fitness, and physical functioning, according to research presented at the American Institute for Cancer Research's Research Conference in Washington, DC.
A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer. The finding suggests that genetic factors can contribute, at last in part, to the higher incidence of prostate cancer among African American men compared with men of other ethnic groups. The team includes scientists at Baylor College of Medicine, Third Military Medical University in China, the Michael E. DeBakey VA Medical Center, and Agilent Technologies India Pvt. Ltd. The study appeared Aug. 31 in Cancer Research.
"African Americans have about one-and-a-half times the incidence and twice the mortality associated with prostate cancer of European Americans, and the reasons for this are not clear," said senior author Dr. Michael Ittmann, professor of pathology & immunology at Baylor and the Michael E. DeBakey Department of VA Medical Center.
In recent days Ben Stiller made headlines for his courageous and honest account of his prostate cancer diagnosis. He speaks candidly about how fortunate he was to have a doctor that did a baseline PSA test, even though it is not recommended by the US Preventive Services Task Force (USPSTF) guidelines. A PSA test is a non-invasive, safe blood test that measures amount of prostate-specific antigen (PSA) in a man’s blood and when monitored over time can be an early indicator of prostate cancer.
Mr. Stiller’s story highlights an issue that for too long has been overlooked. Getting this life-saving test should not come down to which doctor you choose. It should be standard.
A new study offers important information to men who are facing difficult decisions about how to treat prostate cancer in its early stages, or whether to treat it at all.
Researchers followed patients for 10 years and found no difference in death rates between men who were picked at random to have surgery or radiation, or to rely on “active monitoring” of the cancer, with treatment only if it progressed.
Men with very high-risk prostate cancer, who are treated at hospitals with a high proportion of administered radical local treatment (radiotherapy or prostatectomy), only have half of the mortality risk of men who are treated at hospitals with the lowest proportion. This is according to a new study conducted by researchers at Umeå University in Sweden and published in European Urology.
A prostate-specific antigen cut point of ≥0.4 ng/mL predicts future disease progression, according to a study published in The Journal of Urology.
The past five years have seen a torrent of innovation in the treatment of cancer. More than 70 new drugs have come to market, and for some of these describing their consequences as revolutionary is not hyperbole—at least for those patients lucky enough to respond to them. A diagnosis of advanced melanoma, for example, was once tantamount to a death warrant. Median life expectancy after such news was six to nine months. But recently developed “immuno-oncology” drugs, which exploit a patient’s immune system to fight his tumours, are so effective that, in around a fifth of cases, there is real debate among experts as to whether the patient has actually been cured.
A study on non-coding RNA (Ribonucleic Acid) from prostate cancer patients has identified a series of new prostate cancer markers which can be found in urine. Combining these RNA markers into a single test potentially opens the door for simple, accurate non-invasive testing for prostate cancer. This work is presented at the European Association of Urology Congress in Munich.
In March, the Centers for Medicare and Medicaid Services temporarily suspended the development of a proposed “Non-Recommended Prostate-Specific Antigen (PSA)–Based Screening” measure that would discourage PSA screening in all men. The U.S. Preventive Services Task Force (USPSTF) is currently in the process of updating its recommendations for prostate-cancer screening. The decisions made by these two organizations are likely to determine the fate of PSA screening in the United States.
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